I spent some of the most enjoyable years of my life earning my M. Phil. and Ph.D. in L. Nicholas Ornston’s laboratory at Yale University. Bruce Ames at U.C. Berkeley and with Herbert Boyer and Howard Goodman at U.C. San Francisco Medical School provided excellent post-doctoral training.
I had an exceptional undergraduate experience at the University of Illinois (Champaign), carrying out research with Roderick McCleod and Elie Reichmann and was wisely advised by Judy Willis and David Nanney.
These seven individuals greatly stimulated my love of science and prepared me for a scientific career. They are also responsible for the broad training I received, which has served me well as I have changed my research focus several times.
Since I joined the Genetics Group at the University of Georgia in 1976 and the Genetics Faculty in 1980, I’ve worked in the fields of plant molecular genetics and the plant cytoskeleton, RNA and purine metabolism, phytoremediation, chromatin remodeling, obesity, and most recently cell-type specific epigenetic reprogramming in blood, brain, adipose tissues, and placenta.
My wife Valerie Maples works in a nearby laboratory in the Genetics Department and we’ve really enjoyed raising our family in Athens.
Richard B. Meagher, M.Phil., Ph.D.
Distinguished Research Professor in Genetics Room B402A Davison Life Sciences Bld.
University of Georgia, Athens, GA 30602
2011 to present
Epigenetic reprogramming in humans and mammalian models in response to environment (e.g., diet, exercise, stress, sleep, carcinogens) and the epigenome induced risk of disease (i.e., cancer, cardiovascular disease, metabolic syndrome, obesity). We have a strong interest in solving the technical issues associated with performing cell-type-specific epigenetic analyses on “difficult” organs including blood, brain, adipose tissues, and the placenta.
2010 to present
Evolution, multigenerational inheritance, and chemical turnover of epigenetic information
2002 to present
Epigenetics and chromatin remodeling machinery as they impact development and reproduction.
1979 to 2014
The plant actin-based cytoskeleton and the evolution of gene families as its contingent relationship to the macroevolution of various plant organs and tissues.
1980 to 2005
Phytoremediation - The theory behind and the engineering of plants that extract and detoxify mercury and arsenic contaminating our soil and water.
1982 to 2000
RNA turnover as it regulates gene expression and light regulated carbon fixation
1969 to 1972
The protein chemistry and evolution of enzymes catabolizing aromatic compounds in bacteria
1967 to 1969
The molecular biology of double stranded RNA viruses replicating in both plant and insect hosts
Richard B. Meagher Distinguished Research Professor in Genetics
Here is Dr. Meagher’s profile at Google Scholar for an updated list of his ~200 reviewed publications starting in 1972
|Institution and Location||Degree||Years||Fields of Study|
|University of Illinois, Champaign, IL||B.S.||1965-1969||Biology with Honors, Physical Chemistry|
|Yale University, New Haven, CT||M. Phil.||1969-1971||Biology, Biochemistry|
|Yale University, New Haven, CT||Ph.D.||1971-1973||Biology, Enzymology|
Funding during the last 3 years from a total of ~$18,000,000, while at UGA.
|2012||$39,891||NAT INST OF HEALTH SBIR/Sub||Semi-targeted Immuno-Therapeutic Approach to Control Morbid Obesity|
|2012||$300,000||NAT INST OF HEALTH||Affinity Tagging of Adipocyte Nuclei to Examine the Epigenetic Controls of Obesity|
|2013||$300,000||NAT INST OF HEALTH||Affinity Tagging of Adipocyte Nuclei to Examine the Epigenetic Controls of Obesity|
|2014||$356,000||NAT INST OF HEALTH||Nuclear Capture for the Cell-Type Specific Epigenetic Analysis of Adipocytes|
|2014||$25,000||UGA Obesity Initiative||MOUSE XENOGRAFT MODEL FOR HUMAN CELL ADIPOGENESIS|
|2014||$25,000||UGA Obesity Initiative||SLEEP APNEA AND OBESITY EXACERBATE CARDIOVASCULAR DISEASE VIA EPIGENETIC MECHANISMS|
|2014||$25,000||UGA Obesity Initiative||EFFECT OF OBESITY AND FOLIC ACID SUPPLEMENTATION ON GENE-SPECIFIC DNA METHYLATION IN WOMEN OF REPRODUCTIVE AGE: PILOT STUDY|
|2014||$25,000||UGA Obesity Initiative||EXERCISE-INDUCED ADIPOCYTE-SPECIFIC EPIGENETIC REPROGRAMMING IN AN OBESE RAT MODEL|
|2015||$75,000||UGA OVPR IPD||Sleep Apnea and Obesity Exacerbate the Epigenomic Risk of Disease|
|2015||$52,000||UGA OVPR IPD||Effect of maternal obesity on maternal and fetal epigenetic responses to prenatal folic acid doses and impact on early infant growth rate|
|2015||$314,000||NAT INST OF HEALTH||Nuclear Capture for the Cell-Type Specific Epigenetic Analysis of Adipocytes|
Videos in which Dr. Meagher explains his research:
A UGA produced video in which Rich describes his new approach to the cell type specific analysis of fat cells (adipocytes).
Segment from National Geographic’s TV series “Strange Days on Planet Earth” Part 4 in which Rich describes his research developing the phytoremediation of environmental mercury. The producers do a nice job of explaining the concept of phytoremediation, even using cartoons to illustrate what goes on in water and soil. Total time 6 minutes: 30 to 36 min of a 54 min video
Segment from Japanese Public Television in which Rich describes his research into the phytoremediation of environmental mercury contamination. The Japanese have a particular interest in the subject because of its relevance to the Minamata Bay mercury poisoning disaster.